Natural and nature-inspired stilbenoids as antiviral agents

Investigation of Stilbenoids as Potential Therapeutic Agents for Rotavirus Gastroenteritis

Rotavirus (RV) infections cause severe diarrhea in infants and young children worldwide. Vaccines are available but cost prohibitive for many countries and only reduce severe symptoms. Vaccinated infants continue to shed infectious particles, and studies show decreased efficacy of the RV vaccines in tropical and subtropical countries where they are needed most. Continuing surveillance for new R...

Designing and Creating a Mouse Using Nature-Inspired Shapes

Human beings have always made their tools and instruments they need using patterns in nature. Mimicking nature has become the foundation of a new science called Biomimetics. In the present article, multiple forms and levels in nature were utilized to design and create a mouse. The rivers are a good source for choosing the shape of a mouse with lots of stones abraded through the centuries which ...

Protease inhibitors as antiviral agents.

Currently, there are a number of approved antiviral agents for use in the treatment of viral infections. However, many instances exist in which the use of a second antiviral agent would be beneficial because it would allow the option of either an alternative or a combination therapeutic approach. Accordingly, virus-encoded proteases have emerged as new targets for antiviral intervention. Molecu...

Part I Examples of Natural and Nature - Inspired Materials

Cobalt Complexes as Antiviral and Antibacterial Agents

Metal ion complexes are playing an increasing role in the development of antimicrobials. We review here the antimicrobial properties of cobalt coordination complexes in oxidation state 3+. In addition to reviewing the cobalt complexes containing polydentate donor ligands, we also focus on the antimicrobial activity of the homoleptic [Co(NH₃)₆]3+ ion.